Biocompatibility and Effectiveness Evaluation of a New Hemostatic Embolization Agent: Thrombin Loaded Alginate Calcium Microsphere
نویسندگان
چکیده
منابع مشابه
Biocompatibility and Effectiveness Evaluation of a New Hemostatic Embolization Agent: Thrombin Loaded Alginate Calcium Microsphere
Background. Until now, there has been no ideal embolization agent for hemorrhage in interventional treatment. In this study, the thrombin was encapsulated in alginate calcium microsphere using electrostatic droplet technique to produce new embolization agent: thrombin loaded alginate calcium microspheres (TACMs). Objectives. The present work was to evaluate the biocompatibility and hemostatic e...
متن کاملPreparation and Evaluation of Ketoprofen-loaded Calcium alginate beads
Ionotropic gelation method was used to entrap Ketoprofen (KP) into calcium alginate beads. KP is one of the non steroidal anti-inflammatory drugs (NSAIDs); it has a short half life (1.5-2 h) and deleterious side effects on GIT such as irritation and ulceration. Beads were investigated in-vitro for possible sustained drug release and in-vivo as a gastro-protective system for KP. The curing time ...
متن کاملNovel gelatin–alginate surgical sealants loaded with hemostatic agents
Surgical sealants are an integral part of the surgical toolbox. They are used mainly to seal tissues or suture lines. In the current research, we examined a novel surgical sealant based on the natural polymers gelatin and alginate, crosslinked with carbodiimide and loaded with hemostatic agents. Incorporation of the hemostatic agent montmorillonite significantly improved the ex vivo burst stren...
متن کاملIn vivo stability and biocompatibility of implanted calcium alginate disks.
Alginate is a commonly used biomedical hydrogel whose in vivo degradation behavior is only beginning to be understood. The use of alginate in the central nervous system is gaining popularity as an electrode coating, cell encapsulation matrix, and for duraplasty. However, it is necessary to understand how the hydrogel will behave in vivo to aid in the development of alginate for use as a neural ...
متن کاملEvaluation of Biocompatibility and Release Profile of Ginger Extract Loaded Hyaluronic Acid Nanocapsules for Medical Applications
Introduction: Ginger is a plant that is used as a drug for pain relieving and anti-inflammatory in traditional medicine, but conventional prescribing of it faces serious challenges. One way to overcome these problems is the loading of ginger extract in polymer carriers. The aim of this study was characterization and evaluation of the loading and releasing of ginger extract from hyaluronic acid ...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: BioMed Research International
سال: 2017
ISSN: 2314-6133,2314-6141
DOI: 10.1155/2017/1875258